Producer: LLC Vips-Med Russia
Code of automatic telephone exchange: R01AA07
Release form: Liquid dosage forms. Drops. Spray nasal.
General characteristics. Structure:
Active ingredient: 0,5 mg or 1 mg of xylomethazolinum (in the form of a hydrochloride) in 1 ml of solution.
Excipients: a benzalkoniya chloride, dinatrium эдетат (Trilonum of B), potassium dihydrophosphate (potassium phosphate monosubstituted), hydrophosphate sodium dodecahydrate (sodium phosphate disubstituted), sodium chloride, the water purified.
Pharmacodynamics. Xylomethazolinum concerns to group of local vasoconstrictors (decongestants) with an alpha adrenomimeticheskoy activity, causes narrowing of blood vessels of a mucous membrane of a nose, eliminating, thus, hypostasis and a hyperemia of a mucous membrane of a nose, recovers passability of the nasal courses, facilitates nasal breath.
Effect of drug comes in a few minutes after its use and continues till 10 o'clock.
Pharmacokinetics. At topical administration drug is practically not absorbed therefore its concentration in a blood plasma are very small (by modern analytical methods are not defined).
Indications to use:
Acute respiratory diseases with the phenomena of rhinitis (cold); acute allergic rhinitis, sinusitis, pollinosis; average otitis (as a part of a combination therapy for reduction of hypostasis of a mucous nasopharynx); training of the patient for diagnostic manipulations (rinoskopiya).
Route of administration and doses:
Intranazalno. To adults and children 6 years on 1 injection of 0,1% of solution of xylomethazolinum in each nasal course 2-3 times a day are more senior.
To children aged from 2 up to 6 years apply 0,05% xylomethazolinum solution on 1 injection in each nasal course 1-2 times a day.
It is not necessary to use drug more often than 3 times a day. Not to use drug without interruption more than 3-5 days.
Features of use:
Pregnancy and lactation: contraindicated.
Before use it is necessary to clear the nasal courses.
It is not necessary to apply for a long time, for example, at chronic rhinitis.
Influence on ability to manage vehicles and mechanisms: it is not described
At frequent and/or prolonged use - irritation and/or dryness of a mucous membrane of a nasopharynx, burning, paresthesias, sneezing, hypersecretion; seldom - a rhinedema, heartbeat, tachycardia, arrhythmia, increase in arterial pressure, vomiting, a headache, sleeplessness, a vision disorder, a depression (at prolonged use of high doses).
Interaction with other medicines:
It is incompatible with MAO inhibitors and tricyclic antidepressants.
Hypersensitivity to xylomethazolinum, arterial hypertension, tachycardia, the expressed atherosclerosis, glaucoma, atrophic rhinitis, a thyrotoxicosis, surgical interventions on a meninx (in the anamnesis), children's age up to 2 years for use of 0,05% of solution and up to 6 years - for 0,1% of solution.
Not to apply at therapy by inhibitors of monoamine of a ksidaza (MAO) and tricyclic antidepressants.
Symptoms: strengthening of side effects.
At a temperature from 0 to 25 °C in the dry, protected from light place. To store in the place, unavailable to children. A period of validity - 3 years. Not to apply after a period of validity.
According to the recipe
Spray of nasal 0,05%, 0,1%. On 10, 20 ml in the bottles of neutral glass corked by the blooming microsprayer, a raspylitelny nozzle and a protective cap. One bottle in a pack from a cardboard bandbox.